General information
PDB ID 6FTX
Title STRUCTURE OF THE CHROMATIN REMODELLING ENZYME CHD1 BOUND TO A UBIQUITINYLATED NUCLEOSOME
PDB header MOTOR PROTEIN
Date 2018-02-25
Experimental method ELECTRON MICROSCOPY
Resolution (A) 4.5
Kind dna
Organism PETROMYZON MARINUS, XENOPUS LAEVIS, XENOPUS TROPICALIS, SYNTHETIC CONSTRUCT, HOMO SAPIENS, SACCHAROMYCES CEREVISIAE
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6ftx.pdb ABCDEFGHNOW IJ 0
Biounits:
6ftx.pdb1.pdb ABCDEFGHNOW IJ 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Histone Domain S4RAZ3_62-155 7.9e-46 1 CL0012 A 38 131 IJ   
CENP-T_C Domain P62799_18-99 4.9e-08 1 CL0012 B 25 98 IJ   
Histone Domain P06897_19-91 1.2e-15 1 CL0012 C 16 90 I   
Histone Domain Q28D68_32-102 7.2e-22 1 CL0012 D 28 98 I   
Histone Domain P02302_30-132 1.4e-45 1 CL0012 E 27 131 IJ   
CENP-T_C Domain P62799_18-99 6e-08 1 CL0012 F 17 98 IJ   
Histone Domain P06897_19-91 8.9e-16 1 CL0012 G 14 90 IJ   
Histone Domain Q28D68_32-102 1.1e-21 1 CL0012 H 29 98 IJ   
ubiquitin Domain P0CG47_155-226 5.5e-35 1 CL0072 N 3 74   
ubiquitin Domain P0CG47_155-226 5.5e-35 1 CL0072 O 3 74   
SNF2-rel_dom Domain P32657_379-665 2.4e-65 1 CL0023 W 379 665 I   
Cdh1_DBD_1 Domain P32657_1010-1129 2.3e-45 1 CL0123 W 1009 1128 IJ   
Helicase_C Domain P32657_695-809 1.5e-19 1 CL0023 W 695 809 J   
Chromo Domain P32657_285-341 8.2e-15 1 CL0049 W 285 341   
Chromo Domain P32657_178-248 8.6e-07 1 CL0049 W 178 248   
Myb_DNA-binding Domain P32657_988-1017 4.2e-05 0 CL0123 W 1171 1200   
Histone_H2A_C Family P06897_92-120 2.9e-17 1 No_clan C 91 118   
Histone_H2A_C Family P06897_92-120 3e-17 1 No_clan G 91 118   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
B/F=1-103 C host cell nucleus
B/F=1-103 C nucleosome
B/F=1-103 C nucleus
B/F=1-103 F DNA binding
B/F=1-103 F protein heterodimerization activity
B/F=1-103 P DNA-templated transcription, initiation
C/G=1-130 C nucleosome
C/G=1-130 C nucleus
C/G=1-130 F DNA binding
C/G=1-130 F protein heterodimerization activity
E=30-136 C nucleosome
E=30-136 C nucleus
E=30-136 F DNA binding
E=30-136 F protein heterodimerization activity
N/O=1-76 C cytoplasm
N/O=1-76 C cytosol
N/O=1-76 C endocytic vesicle membrane
N/O=1-76 C endoplasmic reticulum membrane
N/O=1-76 C endosome membrane
N/O=1-76 C extracellular exosome
N/O=1-76 C extracellular space
N/O=1-76 C host cell
N/O=1-76 C mitochondrial outer membrane
N/O=1-76 C mitochondrion
N/O=1-76 C neuron projection
N/O=1-76 C neuronal cell body
N/O=1-76 C nucleoplasm
N/O=1-76 C nucleus
N/O=1-76 C plasma membrane
N/O=1-76 C vesicle
N/O=1-76 F protein tag
N/O=1-76 F ubiquitin protein ligase binding
N/O=1-76 P activation of MAPK activity
N/O=1-76 P anaphase-promoting complex-dependent catabolic process
N/O=1-76 P cellular protein metabolic process
N/O=1-76 P cytokine-mediated signaling pathway
N/O=1-76 P DNA damage response, detection of DNA damage
N/O=1-76 P endosomal transport
N/O=1-76 P energy homeostasis
N/O=1-76 P error-free translesion synthesis
N/O=1-76 P error-prone translesion synthesis
N/O=1-76 P fat pad development
N/O=1-76 P female gonad development
N/O=1-76 P female meiosis I
N/O=1-76 P global genome nucleotide-excision repair
N/O=1-76 P hypothalamus gonadotrophin-releasing hormone neuron development
N/O=1-76 P I-kappaB kinase/NF-kappaB signaling
N/O=1-76 P interleukin-1-mediated signaling pathway
N/O=1-76 P interstrand cross-link repair
N/O=1-76 P intracellular transport of virus
N/O=1-76 P JNK cascade
N/O=1-76 P male meiosis I
N/O=1-76 P membrane organization
N/O=1-76 P mitochondrion transport along microtubule
N/O=1-76 P modification-dependent protein catabolic process
N/O=1-76 P MyD88-dependent toll-like receptor signaling pathway
N/O=1-76 P MyD88-independent toll-like receptor signaling pathway
N/O=1-76 P negative regulation of apoptotic process
N/O=1-76 P negative regulation of transcription by RNA polymerase II
N/O=1-76 P negative regulation of transforming growth factor beta receptor signaling pathway
N/O=1-76 P neuron projection morphogenesis
N/O=1-76 P nucleotide-binding oligomerization domain containing signaling pathway
N/O=1-76 P nucleotide-excision repair, DNA damage recognition
N/O=1-76 P nucleotide-excision repair, DNA duplex unwinding
N/O=1-76 P nucleotide-excision repair, DNA gap filling
N/O=1-76 P nucleotide-excision repair, DNA incision
N/O=1-76 P nucleotide-excision repair, DNA incision, 5'-to lesion
N/O=1-76 P nucleotide-excision repair, preincision complex assembly
N/O=1-76 P positive regulation of apoptotic process
N/O=1-76 P positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
N/O=1-76 P positive regulation of NF-kappaB transcription factor activity
N/O=1-76 P positive regulation of protein monoubiquitination
N/O=1-76 P positive regulation of protein ubiquitination
N/O=1-76 P positive regulation of transcription by RNA polymerase II
N/O=1-76 P protein deubiquitination
N/O=1-76 P protein polyubiquitination
N/O=1-76 P protein targeting to peroxisome
N/O=1-76 P protein ubiquitination
N/O=1-76 P regulation of mitochondrial membrane potential
N/O=1-76 P regulation of mRNA stability
N/O=1-76 P regulation of neuron death
N/O=1-76 P regulation of proteasomal protein catabolic process
N/O=1-76 P regulation of transcription from RNA polymerase II promoter in response to hypoxia
N/O=1-76 P seminiferous tubule development
N/O=1-76 P stress-activated MAPK cascade
N/O=1-76 P transcription-coupled nucleotide-excision repair
N/O=1-76 P transforming growth factor beta receptor signaling pathway
N/O=1-76 P translesion synthesis
N/O=1-76 P transmembrane transport
N/O=1-76 P TRIF-dependent toll-like receptor signaling pathway
N/O=1-76 P viral life cycle
N/O=1-76 P virion assembly
N/O=1-76 P Wnt signaling pathway
W=175-1269 C mitochondrion
W=175-1269 C nuclear chromatin
W=175-1269 C nucleolar chromatin
W=175-1269 C SAGA complex
W=175-1269 C SLIK (SAGA-like) complex
W=175-1269 F ATP binding
W=175-1269 F chromatin DNA binding
W=175-1269 F DNA binding
W=175-1269 F DNA-dependent ATPase activity
W=175-1269 F helicase activity
W=175-1269 F methylated histone binding
W=175-1269 F nucleosome-dependent ATPase activity
W=175-1269 F rDNA binding
W=175-1269 F transcription regulatory region sequence-specific DNA binding
W=175-1269 P ATP-dependent chromatin remodeling
W=175-1269 P histone H2B conserved C-terminal lysine ubiquitination
W=175-1269 P negative regulation of DNA-dependent DNA replication
W=175-1269 P negative regulation of histone exchange
W=175-1269 P negative regulation of histone H3-K14 acetylation
W=175-1269 P negative regulation of histone H3-K9 acetylation
W=175-1269 P nucleosome mobilization
W=175-1269 P nucleosome organization
W=175-1269 P nucleosome positioning
W=175-1269 P regulation of chromatin organization
W=175-1269 P regulation of nucleosome density
W=175-1269 P regulation of transcriptional start site selection at RNA polymerase II promoter
W=175-1269 P sister chromatid cohesion
W=175-1269 P termination of RNA polymerase I transcription
W=175-1269 P termination of RNA polymerase II transcription
W=175-1269 P transcription elongation from RNA polymerase II promoter
Sequences
Download file with secondary structure created by Stride  
6ftx.pdb1.pdb:   [ download sequences in FASTA format ]
I (dna): 
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J (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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E (protein): 
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F (protein): 
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G (protein): 
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H (protein): 
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N (protein): 
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O (protein): 
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W (protein): 
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