General information
PDB ID 6HT5
Title OCT4/SOX2:UTF1 STRUCTURE
PDB header TRANSCRIPTION
Date 2018-10-03
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.45
Kind dna
Organism MUS MUSCULUS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6ht5.pdb DE AB 0
Biounits:
6ht5.pdb1.pdb DE AB 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
HMG_box Domain P48432_43-111 5.7e-29 1 CL0114 D 46 114 AB  H-Bb H-Mj H-Mn L-Bb L-Mn 
Pou Domain P20263_134-205 9e-35 1 CL0123 E 136 207 AB  H-Bb H-Mj L-Bb 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
D=41-120 C cytoplasm
D=41-120 C cytosol
D=41-120 C nucleoplasm
D=41-120 C nucleus
D=41-120 C transcription regulator complex
D=41-120 F chromatin binding
D=41-120 F chromatin DNA binding
D=41-120 F DNA binding
D=41-120 F DNA-binding transcription factor activity
D=41-120 F DNA-binding transcription factor activity, RNA polymerase II-specific
D=41-120 F miRNA binding
D=41-120 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
D=41-120 F sequence-specific DNA binding
D=41-120 F transcription factor binding
D=41-120 F transcription regulatory region sequence-specific DNA binding
D=41-120 P adenohypophysis development
D=41-120 P anatomical structure formation involved in morphogenesis
D=41-120 P anatomical structure morphogenesis
D=41-120 P cell cycle arrest
D=41-120 P cell differentiation
D=41-120 P cell fate commitment
D=41-120 P cell fate specification
D=41-120 P cerebral cortex development
D=41-120 P detection of mechanical stimulus involved in equilibrioception
D=41-120 P detection of mechanical stimulus involved in sensory perception of sound
D=41-120 P diencephalon morphogenesis
D=41-120 P embryonic organ development
D=41-120 P endodermal cell fate specification
D=41-120 P epithelial tube branching involved in lung morphogenesis
D=41-120 P forebrain development
D=41-120 P forebrain neuron differentiation
D=41-120 P inner ear development
D=41-120 P inner ear morphogenesis
D=41-120 P lens induction in camera-type eye
D=41-120 P lung alveolus development
D=41-120 P male genitalia development
D=41-120 P negative regulation of canonical Wnt signaling pathway
D=41-120 P negative regulation of cell differentiation
D=41-120 P negative regulation of epithelial cell proliferation
D=41-120 P negative regulation of neuron differentiation
D=41-120 P negative regulation of osteoblast differentiation
D=41-120 P negative regulation of transcription by RNA polymerase II
D=41-120 P negative regulation of Wnt signaling pathway
D=41-120 P neuron fate commitment
D=41-120 P neuronal stem cell population maintenance
D=41-120 P olfactory placode formation
D=41-120 P osteoblast differentiation
D=41-120 P pigment biosynthetic process
D=41-120 P positive regulation of cell differentiation
D=41-120 P positive regulation of cell-cell adhesion
D=41-120 P positive regulation of epithelial cell differentiation
D=41-120 P positive regulation of MAPK cascade
D=41-120 P positive regulation of neuroblast proliferation
D=41-120 P positive regulation of neuron differentiation
D=41-120 P positive regulation of Notch signaling pathway
D=41-120 P positive regulation of transcription by RNA polymerase II
D=41-120 P positive regulation of transcription, DNA-templated
D=41-120 P regulation of cysteine-type endopeptidase activity involved in apoptotic process
D=41-120 P regulation of gene expression
D=41-120 P regulation of neurogenesis
D=41-120 P regulation of transcription by RNA polymerase II
D=41-120 P regulation of transcription, DNA-templated
D=41-120 P response to growth factor
D=41-120 P response to organic substance
D=41-120 P response to retinoic acid
D=41-120 P retina morphogenesis in camera-type eye
D=41-120 P sensory perception of sound
D=41-120 P somatic stem cell population maintenance
D=41-120 P stem cell differentiation
D=41-120 P stem cell population maintenance
D=41-120 P tongue development
E=131-282 C cytoplasm
E=131-282 C cytosol
E=131-282 C mitochondrion
E=131-282 C nuclear chromatin
E=131-282 C nucleolus
E=131-282 C nucleoplasm
E=131-282 C nucleus
E=131-282 C transcription regulator complex
E=131-282 C transcription repressor complex
E=131-282 F chromatin binding
E=131-282 F chromatin DNA binding
E=131-282 F cis-regulatory region sequence-specific DNA binding
E=131-282 F cytokine binding
E=131-282 F DNA binding
E=131-282 F DNA-binding transcription activator activity, RNA polymerase II-specific
E=131-282 F DNA-binding transcription factor activity
E=131-282 F DNA-binding transcription factor activity, RNA polymerase II-specific
E=131-282 F DNA-binding transcription repressor activity, RNA polymerase II-specific
E=131-282 F HMG box domain binding
E=131-282 F miRNA binding
E=131-282 F POU domain binding
E=131-282 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
E=131-282 F RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
E=131-282 F sequence-specific DNA binding
E=131-282 F sequence-specific double-stranded DNA binding
E=131-282 F transcription coactivator activity
E=131-282 F transcription corepressor activity
E=131-282 F transcription factor binding
E=131-282 F transcription regulatory region sequence-specific DNA binding
E=131-282 F ubiquitin protein ligase binding
E=131-282 P blastocyst development
E=131-282 P blastocyst growth
E=131-282 P BMP signaling pathway involved in heart induction
E=131-282 P cardiac cell fate determination
E=131-282 P cell differentiation
E=131-282 P cell fate commitment
E=131-282 P cell fate commitment involved in formation of primary germ layer
E=131-282 P cellular response to leukemia inhibitory factor
E=131-282 P ectodermal cell fate commitment
E=131-282 P endodermal cell fate commitment
E=131-282 P endodermal cell fate specification
E=131-282 P germ-line stem cell population maintenance
E=131-282 P mesodermal cell fate commitment
E=131-282 P negative regulation of calcium ion-dependent exocytosis
E=131-282 P negative regulation of cell differentiation
E=131-282 P negative regulation of gene expression
E=131-282 P negative regulation of gene silencing by miRNA
E=131-282 P negative regulation of pri-miRNA transcription by RNA polymerase II
E=131-282 P negative regulation of protein kinase B signaling
E=131-282 P negative regulation of transcription by RNA polymerase II
E=131-282 P negative regulation of transcription, DNA-templated
E=131-282 P positive regulation of canonical Wnt signaling pathway
E=131-282 P positive regulation of gene expression
E=131-282 P positive regulation of SMAD protein signal transduction
E=131-282 P positive regulation of transcription by RNA polymerase II
E=131-282 P positive regulation of transcription initiation from RNA polymerase II promoter
E=131-282 P positive regulation of transcription, DNA-templated
E=131-282 P regulation of asymmetric cell division
E=131-282 P regulation of DNA methylation-dependent heterochromatin assembly
E=131-282 P regulation of gene expression
E=131-282 P regulation of heart induction by regulation of canonical Wnt signaling pathway
E=131-282 P regulation of transcription by RNA polymerase II
E=131-282 P regulation of transcription, DNA-templated
E=131-282 P response to organic substance
E=131-282 P response to retinoic acid
E=131-282 P somatic stem cell population maintenance
E=131-282 P stem cell differentiation
E=131-282 P stem cell population maintenance
E=131-282 P transcription by RNA polymerase II
E=131-282 P trophectodermal cell differentiation
Sequences
Download file with secondary structure created by Stride  
6ht5.pdb1.pdb:   [ download sequences in FASTA format ]
A (dna): 
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B (dna): 
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D (protein): 
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E (protein): 
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