General information
PDB ID 6HV9
Title S. CEREVISIAE CMG-POL EPSILON-DNA
PDB header DNA BINDING PROTEIN
Date 2018-10-10
Experimental method ELECTRON MICROSCOPY
Resolution (A) 4.98
Kind hybrid
Organism SACCHAROMYCES CEREVISIAE
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
PRIDB
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6hv9.pdb 345627CDEFGBA XYJ XY 0
Biounits:
6hv9.pdb1.pdb 345627CDEFGBA XYJ XY 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
MCM Domain P29469_480-703 1e-87 1 CL0023 2 480 703 J   
MCM_OB Domain P29469_311-434 7.7e-26 1 CL0021 2 295 434   
MCM_lid Domain P29469_761-845 6.4e-24 1 CL0671 2 761 845   
MCM_N Domain P29469_208-299 8.3e-12 1 No_clan 2 208 312   
MCM Domain P24279_346-569 2.5e-94 1 CL0023 3 346 569 J   
MCM_OB Domain P24279_166-302 1.3e-32 1 CL0021 3 137 302   
MCM_lid Domain P24279_654-737 3e-24 1 CL0671 3 654 737   
MCM_N Domain P24279_25-137 7e-08 1 No_clan 3 25 215   
MCM Domain P30665_505-728 1.2e-98 1 CL0023 4 505 728   
MCM_OB Domain P30665_313-443 7.1e-30 1 CL0021 4 313 443   
MCM_lid Domain P30665_745-833 1.2e-25 1 CL0671 4 745 833   
MCM_N Domain P30665_191-299 1.6e-13 1 No_clan 4 191 329   
MCM Domain P29496_353-576 3.2e-99 1 CL0023 5 353 576   
MCM_OB Domain P29496_152-302 4.7e-32 1 CL0021 5 139 302   
MCM_lid Domain P29496_597-688 2.3e-26 1 CL0671 5 597 688   
MCM_N Domain P29496_28-103 5.3e-16 1 No_clan 5 28 165   
MCM Domain P53091_512-735 3.5e-83 1 CL0023 6 512 735   
MCM_OB Domain P53091_275-405 1.5e-40 1 CL0021 6 275 405   
MCM_lid Domain P53091_749-835 2.6e-26 1 CL0671 6 749 835   
MCM_N Domain P53091_112-193 6.1e-19 1 No_clan 6 112 329   
MCM Domain P38132_397-620 8e-79 1 CL0023 7 397 620   
MCM_OB Domain P38132_226-359 3.7e-32 1 CL0021 7 226 359   
MCM_lid Domain P38132_636-724 2.5e-22 1 CL0671 7 636 724   
MCM_N Domain P38132_18-206 2.5e-08 1 No_clan 7 18 206   
DUF1744 Domain P21951_1528-1920 2.7e-65 1 CL0194 A 1528 1785   
SLD5_C Domain Q03406_222-293 2e-18 1 No_clan F 222 293   
DNA_pol_E_B Family P24482_400-651 5.9e-58 1 CL0163 B 399 651   
Sld5 Family Q12488_18-128 5.6e-08 1 No_clan C 27 131   
Sld5 Family P40359_69-178 2.1e-19 1 No_clan D 69 178   
Sld5 Family Q12146_44-174 3.8e-19 1 No_clan E 44 178   
Sld5 Family Q03406_74-180 5.1e-07 1 No_clan F 61 181   
CDC45 Family Q08032_140-539 6.8e-150 1 No_clan G 164 647   
CDC45 Family Q08032_21-146 1.8e-36 1 No_clan G 25 222   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
2=1-868 C CMG complex
2=1-868 C cytoplasm
2=1-868 C DNA replication preinitiation complex
2=1-868 C MCM complex
2=1-868 C nuclear pre-replicative complex
2=1-868 C nucleoplasm
2=1-868 C nucleus
2=1-868 C replication fork protection complex
2=1-868 F ATP binding
2=1-868 F chromatin binding
2=1-868 F DNA helicase activity
2=1-868 F DNA replication origin binding
2=1-868 F metal ion binding
2=1-868 F single-stranded DNA binding
2=1-868 P cellular response to DNA damage stimulus
2=1-868 P DNA strand elongation involved in DNA replication
2=1-868 P DNA unwinding involved in DNA replication
2=1-868 P double-strand break repair via break-induced replication
2=1-868 P mitotic DNA replication initiation
2=1-868 P negative regulation of DNA helicase activity
2=1-868 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
3=1-971 C chromosome, telomeric region
3=1-971 C CMG complex
3=1-971 C cytoplasm
3=1-971 C DNA replication preinitiation complex
3=1-971 C MCM complex
3=1-971 C nuclear pre-replicative complex
3=1-971 C nucleoplasm
3=1-971 C nucleus
3=1-971 C replication fork protection complex
3=1-971 F ATP binding
3=1-971 F chromatin binding
3=1-971 F DNA helicase activity
3=1-971 F DNA replication origin binding
3=1-971 F MCM complex binding
3=1-971 F single-stranded DNA binding
3=1-971 P chromatin silencing at telomere
3=1-971 P DNA replication initiation
3=1-971 P DNA strand elongation involved in DNA replication
3=1-971 P double-strand break repair via break-induced replication
3=1-971 P mitotic DNA replication initiation
3=1-971 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
3=1-971 P silent mating-type cassette heterochromatin assembly
4=1-933 C CMG complex
4=1-933 C cytoplasm
4=1-933 C DNA replication preinitiation complex
4=1-933 C MCM complex
4=1-933 C MCM core complex
4=1-933 C nuclear pre-replicative complex
4=1-933 C nuclear replication fork
4=1-933 C nucleoplasm
4=1-933 C nucleus
4=1-933 C replication fork protection complex
4=1-933 F ATP binding
4=1-933 F DNA helicase activity
4=1-933 F DNA replication origin binding
4=1-933 F single-stranded DNA binding
4=1-933 P DNA replication initiation
4=1-933 P DNA strand elongation involved in DNA replication
4=1-933 P DNA unwinding involved in DNA replication
4=1-933 P double-strand break repair via break-induced replication
4=1-933 P mitotic DNA replication initiation
4=1-933 P nuclear DNA replication
4=1-933 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
4=1-933 P protein hexamerization
5=1-775 C CMG complex
5=1-775 C cytoplasm
5=1-775 C DNA replication preinitiation complex
5=1-775 C MCM complex
5=1-775 C nuclear chromosome, telomeric region
5=1-775 C nuclear pre-replicative complex
5=1-775 C nucleoplasm
5=1-775 C nucleus
5=1-775 C replication fork protection complex
5=1-775 F ATP binding
5=1-775 F chromatin binding
5=1-775 F DNA helicase activity
5=1-775 F DNA replication origin binding
5=1-775 F single-stranded DNA binding
5=1-775 P chromatin silencing at telomere
5=1-775 P DNA replication initiation
5=1-775 P double-strand break repair via break-induced replication
5=1-775 P heterochromatin assembly
5=1-775 P negative regulation of chromatin silencing at telomere
5=1-775 P nuclear DNA replication
5=1-775 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
5=1-775 P regulation of DNA-dependent DNA replication initiation
6=1-1017 C CMG complex
6=1-1017 C cytoplasm
6=1-1017 C DNA replication preinitiation complex
6=1-1017 C MCM complex
6=1-1017 C MCM core complex
6=1-1017 C nuclear pre-replicative complex
6=1-1017 C nucleoplasm
6=1-1017 C nucleus
6=1-1017 C replication fork protection complex
6=1-1017 F ATP binding
6=1-1017 F DNA replication origin binding
6=1-1017 F single-stranded DNA binding
6=1-1017 F single-stranded DNA helicase activity
6=1-1017 P DNA replication initiation
6=1-1017 P DNA strand elongation involved in DNA replication
6=1-1017 P DNA unwinding involved in DNA replication
6=1-1017 P double-strand break repair via break-induced replication
6=1-1017 P mitotic DNA replication
6=1-1017 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
7=1-845 C chromosome, telomeric region
7=1-845 C CMG complex
7=1-845 C cytoplasm
7=1-845 C DNA replication preinitiation complex
7=1-845 C MCM complex
7=1-845 C MCM core complex
7=1-845 C nuclear pre-replicative complex
7=1-845 C nucleoplasm
7=1-845 C nucleus
7=1-845 C replication fork protection complex
7=1-845 F ATP binding
7=1-845 F chromatin binding
7=1-845 F DNA replication origin binding
7=1-845 F MCM complex binding
7=1-845 F single-stranded DNA binding
7=1-845 F single-stranded DNA helicase activity
7=1-845 P chromatin silencing at telomere
7=1-845 P DNA replication initiation
7=1-845 P DNA strand elongation involved in DNA replication
7=1-845 P DNA unwinding involved in DNA replication
7=1-845 P double-strand break repair via break-induced replication
7=1-845 P nuclear DNA replication
7=1-845 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
7=1-845 P silent mating-type cassette heterochromatin assembly
A=1308-2221 C epsilon DNA polymerase complex
A=1308-2221 C replication fork
A=1308-2221 F 4 iron, 4 sulfur cluster binding
A=1308-2221 F DNA binding
A=1308-2221 F DNA-directed DNA polymerase activity
A=1308-2221 F double-stranded DNA binding
A=1308-2221 F mRNA binding
A=1308-2221 F nucleotide binding
A=1308-2221 F single-stranded DNA 3'-5' exodeoxyribonuclease activity
A=1308-2221 F single-stranded DNA binding
A=1308-2221 F SUMO binding
A=1308-2221 F zinc ion binding
A=1308-2221 P base-excision repair
A=1308-2221 P base-excision repair, gap-filling
A=1308-2221 P DNA replication proofreading
A=1308-2221 P DNA-dependent DNA replication
A=1308-2221 P double-strand break repair
A=1308-2221 P double-strand break repair via nonhomologous end joining
A=1308-2221 P error-prone translesion synthesis
A=1308-2221 P gene conversion
A=1308-2221 P heterochromatin organization involved in chromatin silencing
A=1308-2221 P intra-S DNA damage checkpoint
A=1308-2221 P leading strand elongation
A=1308-2221 P mitotic cell cycle
A=1308-2221 P mitotic DNA replication checkpoint
A=1308-2221 P mitotic sister chromatid cohesion
A=1308-2221 P nucleotide-excision repair, DNA gap filling
B=1-689 C cytoplasm
B=1-689 C epsilon DNA polymerase complex
B=1-689 C nucleus
B=1-689 F DNA binding
B=1-689 P cell cycle
B=1-689 P DNA-dependent DNA replication
B=1-689 P DNA-dependent DNA replication maintenance of fidelity
B=1-689 P error-prone translesion synthesis
B=1-689 P heterochromatin organization involved in chromatin silencing
C=1-208 C CMG complex
C=1-208 C DNA replication preinitiation complex
C=1-208 C GINS complex
C=1-208 C replication fork protection complex
C=1-208 P DNA strand elongation involved in mitotic DNA replication
C=1-208 P DNA-dependent DNA replication
C=1-208 P double-strand break repair via break-induced replication
D=1-213 C CMG complex
D=1-213 C DNA replication preinitiation complex
D=1-213 C GINS complex
D=1-213 C nuclear replication fork
D=1-213 C nucleus
D=1-213 C replication fork protection complex
D=1-213 P DNA duplex unwinding
D=1-213 P DNA-dependent DNA replication
D=1-213 P double-strand break repair via break-induced replication
E=1-194 C CMG complex
E=1-194 C DNA replication preinitiation complex
E=1-194 C GINS complex
E=1-194 C replication fork protection complex
E=1-194 P DNA-dependent DNA replication
E=1-194 P double-strand break repair via break-induced replication
F=1-294 C CMG complex
F=1-294 C DNA replication preinitiation complex
F=1-294 C GINS complex
F=1-294 C replication fork protection complex
F=1-294 P DNA duplex unwinding
F=1-294 P DNA-dependent DNA replication
F=1-294 P double-strand break repair via break-induced replication
G=1-650 C CMG complex
G=1-650 C DNA replication preinitiation complex
G=1-650 C nuclear pre-replicative complex
G=1-650 C nuclear replication fork
G=1-650 C nucleus
G=1-650 C replication fork protection complex
G=1-650 F chromatin binding
G=1-650 F DNA replication origin binding
G=1-650 F single-stranded DNA binding
G=1-650 P DNA replication initiation
G=1-650 P double-strand break repair via break-induced replication
G=1-650 P mitotic DNA replication preinitiation complex assembly
G=1-650 P positive regulation of G1/S transition of mitotic cell cycle
G=1-650 P regulation of chromatin silencing at telomere
Sequences
Download file with secondary structure created by Stride  
6hv9.pdb1.pdb:   [ download sequences in FASTA format ]
J (dna): 
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X (hybrid): 
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Y (hybrid): 
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2 (protein): 
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3 (protein): 
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4 (protein): 
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5 (protein): 
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6 (protein): 
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7 (protein): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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E (protein): 
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F (protein): 
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G (protein): 
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