General information
PDB ID 6JM9
Title CRYO-EM STRUCTURE OF DOT1L BOUND TO UNMODIFIED NUCLEOSOME
PDB header GENE REGULATION
Date 2019-03-07
Experimental method ELECTRON MICROSCOPY
Resolution (A) 7.3
Kind dna
Organism SYNTHETIC CONSTRUCT, XENOPUS LAEVIS, HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6jm9.pdb ABCDEFGHX IJ 0
Biounits:
6jm9.pdb1.pdb ABCDEFGHX IJ 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Histone Domain P84233_37-132 3.7e-46 1 CL0012 A 38 131 IJ   
CENP-T_C Domain P62799_26-99 4.7e-08 1 CL0012 B 25 98 IJ   
Histone Domain Q6AZJ8_15-91 9.4e-16 1 CL0012 C 14 90 IJ   
Histone Domain P02281_33-102 1.1e-21 1 CL0012 D 29 98 IJ   
Histone Domain P84233_37-132 3.7e-46 1 CL0012 E 38 131 IJ   
CENP-T_C Domain P62799_18-99 5.2e-08 1 CL0012 F 20 98 IJ   
Histone Domain Q6AZJ8_15-91 9.2e-16 1 CL0012 G 14 90 IJ   
Histone Domain P02281_33-102 1.1e-21 1 CL0012 H 29 98 IJ   
DOT1 Domain Q8TEK3_115-317 9e-84 1 CL0063 X 115 317   
Histone_H2A_C Family Q6AZJ8_92-119 8.1e-19 1 No_clan C 91 120   
Histone_H2A_C Family Q6AZJ8_92-119 4e-18 1 No_clan G 91 119   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/E=39-136 C nucleoplasm
A/E=39-136 C nucleosome
A/E=39-136 F DNA binding
A/E=39-136 F protein heterodimerization activity
B/F=17-103 C host cell nucleus
B/F=17-103 C nucleosome
B/F=17-103 C nucleus
B/F=17-103 F DNA binding
B/F=17-103 F protein heterodimerization activity
B/F=17-103 P DNA-templated transcription, initiation
D/H=34-126 C nucleosome
D/H=34-126 C nucleus
D/H=34-126 F DNA binding
D/H=34-126 F protein heterodimerization activity
X=5-332 C chromosome, telomeric region
X=5-332 C intracellular membrane-bounded organelle
X=5-332 C nucleoplasm
X=5-332 C nucleus
X=5-332 C protein-containing complex
X=5-332 F DNA binding
X=5-332 F histone methyltransferase activity
X=5-332 F histone methyltransferase activity (H3-K79 specific)
X=5-332 F histone-lysine N-methyltransferase activity
X=5-332 F transcription factor binding
X=5-332 P chromatin silencing at telomere
X=5-332 P DNA damage checkpoint
X=5-332 P DNA repair
X=5-332 P histone H3-K79 methylation
X=5-332 P positive regulation of cell population proliferation
X=5-332 P positive regulation of transcription by RNA polymerase II
X=5-332 P regulation of receptor signaling pathway via JAK-STAT
X=5-332 P regulation of transcription regulatory region DNA binding
X=5-332 P telomere organization
Sequences
Download file with secondary structure created by Stride  
6jm9.pdb1.pdb:   [ download sequences in FASTA format ]
I (dna): 
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J (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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E (protein): 
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F (protein): 
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G (protein): 
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H (protein): 
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X (protein): 
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