General information
PDB ID 6NN6
Title STRUCTURE OF DOT1L-H2BK120UB NUCLEOSOME COMPLEX
PDB header GENE REGULATION
Date 2019-01-14
Experimental method ELECTRON MICROSCOPY
Resolution (A) 3.9
Kind dna
Organism XENOPUS LAEVIS, SYNTHETIC CONSTRUCT, HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6nn6.pdb ABCDEFGHKL IJ 0
Biounits:
6nn6.pdb1.pdb ABCDEFGHKL IJ 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Histone Domain P84233_37-132 7.9e-46 1 CL0012 A 38 131 IJ   
CENP-T_C Domain P62799_26-99 4.4e-08 1 CL0012 B 25 98 J   
Histone Domain P06897_19-91 9.8e-16 1 CL0012 C 15 90 IJ   
Histone Domain P02281_33-102 1.1e-21 1 CL0012 D 32 101 IJ   
Histone Domain P84233_37-132 2.5e-45 1 CL0012 E 39 131 IJ   
CENP-T_C Domain P62799_26-99 4.2e-08 1 CL0012 F 26 98 IJ   
Histone Domain P06897_19-91 8.9e-16 1 CL0012 G 14 90 IJ   
Histone Domain P02281_33-102 1.1e-21 1 CL0012 H 32 101 JI   
DOT1 Domain Q8TEK3_115-317 9e-84 1 CL0063 K 115 317   
ubiquitin Domain F5H388_79-150 5e-35 1 CL0072 L 3 74   
Histone_H2A_C Family P06897_92-120 3e-17 1 No_clan C 91 118   
Histone_H2A_C Family P06897_92-120 3e-17 1 No_clan G 91 118   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/E=2-136 C nucleoplasm
A/E=2-136 C nucleosome
A/E=2-136 F DNA binding
A/E=2-136 F protein heterodimerization activity
B/F=2-103 C host cell nucleus
B/F=2-103 C nucleosome
B/F=2-103 C nucleus
B/F=2-103 F DNA binding
B/F=2-103 F protein heterodimerization activity
B/F=2-103 P DNA-templated transcription, initiation
C/G=2-130 C nucleosome
C/G=2-130 C nucleus
C/G=2-130 F DNA binding
C/G=2-130 F protein heterodimerization activity
D/H=5-126 C nucleosome
D/H=5-126 C nucleus
D/H=5-126 F DNA binding
D/H=5-126 F protein heterodimerization activity
K=3-416 C chromosome, telomeric region
K=3-416 C intracellular membrane-bounded organelle
K=3-416 C nucleoplasm
K=3-416 C nucleus
K=3-416 C protein-containing complex
K=3-416 F DNA binding
K=3-416 F histone methyltransferase activity
K=3-416 F histone methyltransferase activity (H3-K79 specific)
K=3-416 F histone-lysine N-methyltransferase activity
K=3-416 F transcription factor binding
K=3-416 P chromatin silencing at telomere
K=3-416 P DNA damage checkpoint
K=3-416 P DNA repair
K=3-416 P histone H3-K79 methylation
K=3-416 P positive regulation of cell population proliferation
K=3-416 P positive regulation of transcription by RNA polymerase II
K=3-416 P regulation of receptor signaling pathway via JAK-STAT
K=3-416 P regulation of transcription regulatory region DNA binding
K=3-416 P telomere organization
Sequences
Download file with secondary structure created by Stride  
6nn6.pdb1.pdb:   [ download sequences in FASTA format ]
I (dna): 
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J (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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E (protein): 
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F (protein): 
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G (protein): 
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H (protein): 
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K (protein): 
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L (protein): 
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