General information
PDB ID 6SE6
Title CLASS2 : CENP-A NUCLEOSOME IN COMPLEX WITH CENP-C CENTRAL REGION
PDB header NUCLEAR PROTEIN
Date 2019-07-29
Experimental method ELECTRON MICROSCOPY
Resolution (A) 3.5
Kind dna
Organism HOMO SAPIENS, SYNTHETIC CONSTRUCT
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6se6.pdb ABCDEFGHV IJ 0
Biounits:
6se6.pdb1.pdb ABCDEFGHV IJ 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Histone Domain P49450_42-133 2.9e-34 1 CL0012 A 42 133 IJ   
CENP-T_C Domain P62805_26-99 4.7e-08 1 CL0012 B 25 98 IJ   
Histone Domain Q6FI13_17-91 5.6e-16 1 CL0012 C 16 90 IJ   
Histone Domain P62807_33-102 3.1e-21 1 CL0012 D 33 101 IJ   
Histone Domain P49450_42-133 2.9e-34 1 CL0012 E 42 133 IJ   
CENP-T_C Domain P62805_19-99 5.1e-08 1 CL0012 F 25 98 IJ   
Histone Domain Q6FI13_10-91 1.5e-16 1 CL0012 G 10 90 IJ   
Histone Domain P62807_33-102 8.6e-21 1 CL0012 H 35 101 IJ   
Histone_H2A_C Family Q6FI13_92-117 2.3e-15 1 No_clan C 91 116   
Histone_H2A_C Family Q6FI13_92-117 2.9e-16 1 No_clan G 91 117   
CENP-C_mid Family Q03188_520-537 3.4e-07 1 No_clan V 519 536   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/E=1-140 C chromosome, centromeric region
A/E=1-140 C condensed chromosome inner kinetochore
A/E=1-140 C condensed nuclear chromosome kinetochore
A/E=1-140 C condensed nuclear chromosome, centromeric region
A/E=1-140 C cytosol
A/E=1-140 C nuclear nucleosome
A/E=1-140 C nuclear pericentric heterochromatin
A/E=1-140 C nucleoplasm
A/E=1-140 C nucleus
A/E=1-140 F chromatin binding
A/E=1-140 F DNA binding
A/E=1-140 F protein heterodimerization activity
A/E=1-140 P CENP-A containing nucleosome assembly
A/E=1-140 P establishment of mitotic spindle orientation
A/E=1-140 P kinetochore assembly
A/E=1-140 P mitotic cytokinesis
A/E=1-140 P protein localization to chromosome, centromeric region
A/E=1-140 P viral process
B/F=1-103 C extracellular exosome
B/F=1-103 C extracellular region
B/F=1-103 C host cell nucleus
B/F=1-103 C membrane
B/F=1-103 C nuclear chromosome
B/F=1-103 C nuclear chromosome, telomeric region
B/F=1-103 C nuclear nucleosome
B/F=1-103 C nucleoplasm
B/F=1-103 C nucleosome
B/F=1-103 C nucleus
B/F=1-103 C protein-containing complex
B/F=1-103 F DNA binding
B/F=1-103 F protein domain specific binding
B/F=1-103 F protein heterodimerization activity
B/F=1-103 F RNA binding
B/F=1-103 P cellular protein metabolic process
B/F=1-103 P CENP-A containing nucleosome assembly
B/F=1-103 P DNA replication-dependent nucleosome assembly
B/F=1-103 P DNA replication-independent nucleosome assembly
B/F=1-103 P DNA-templated transcription, initiation
B/F=1-103 P double-strand break repair via nonhomologous end joining
B/F=1-103 P negative regulation of gene expression, epigenetic
B/F=1-103 P negative regulation of megakaryocyte differentiation
B/F=1-103 P nucleosome assembly
B/F=1-103 P rDNA heterochromatin assembly
B/F=1-103 P regulation of gene silencing by miRNA
B/F=1-103 P regulation of megakaryocyte differentiation
B/F=1-103 P telomere capping
B/F=1-103 P telomere organization
C/G=1-130 C extracellular exosome
C/G=1-130 C nuclear chromatin
C/G=1-130 C nucleosome
C/G=1-130 C nucleus
C/G=1-130 F DNA binding
C/G=1-130 F protein heterodimerization activity
C/G=1-130 P chromatin organization
C/G=1-130 P chromatin silencing
D/H=1-126 C cytosol
D/H=1-126 C extracellular exosome
D/H=1-126 C extracellular space
D/H=1-126 C nucleoplasm
D/H=1-126 C nucleosome
D/H=1-126 C nucleus
D/H=1-126 F DNA binding
D/H=1-126 F identical protein binding
D/H=1-126 F protein heterodimerization activity
D/H=1-126 P antibacterial humoral response
D/H=1-126 P antimicrobial humoral immune response mediated by antimicrobial peptide
D/H=1-126 P defense response to Gram-positive bacterium
D/H=1-126 P innate immune response in mucosa
D/H=1-126 P nucleosome assembly
D/H=1-126 P protein ubiquitination
V=426-537 C condensed nuclear chromosome kinetochore
V=426-537 C condensed nuclear chromosome, centromeric region
V=426-537 C cytosol
V=426-537 C kinetochore
V=426-537 C midbody
V=426-537 C nuclear body
V=426-537 C nucleoplasm
V=426-537 C pericentric heterochromatin
V=426-537 F centromeric DNA binding
V=426-537 F DNA binding
V=426-537 F identical protein binding
V=426-537 P attachment of mitotic spindle microtubules to kinetochore
V=426-537 P cell division
V=426-537 P CENP-A containing nucleosome assembly
V=426-537 P chromosome segregation
V=426-537 P kinetochore assembly
V=426-537 P mitotic cell cycle
V=426-537 P monopolar spindle attachment to meiosis I kinetochore
Sequences
Download file with secondary structure created by Stride  
6se6.pdb1.pdb:   [ download sequences in FASTA format ]
I (dna): 
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J (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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E (protein): 
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F (protein): 
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G (protein): 
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H (protein): 
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V (protein): 
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