General information
PDB ID 6SKO
Title CRYO-EM STRUCTURE OF THE FORK PROTECTION COMPLEX BOUND TO CMG AT A REPLICATION FORK - CONFORMATION 2 MCM CTD:SSDNA
PDB header REPLICATION
Date 2019-08-16
Experimental method ELECTRON MICROSCOPY
Resolution (A) 3.4
Kind dna
Organism SYNTHETIC CONSTRUCT
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6sko.pdb 672534 I 0
Biounits:
6sko.pdb1.pdb 672534 I 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
MCM Domain P29469_480-703 7.2e-91 1 CL0023 2 480 703 I   
MCM_lid Domain P29469_761-845 5.4e-25 1 CL0671 2 761 845   
MCM Domain P24279_346-569 4.5e-95 1 CL0023 3 346 569 I   
MCM_lid Domain P24279_654-737 1.3e-24 1 CL0671 3 654 737   
MCM Domain P30665_505-728 5.7e-97 1 CL0023 4 505 728 I   
MCM_lid Domain P30665_745-833 3e-25 1 CL0671 4 745 833   
MCM Domain P29496_353-576 2.5e-65 1 CL0023 5 353 546 I   
MCM_lid Domain P29496_597-688 1.1e-25 1 CL0671 5 597 687   
MCM Domain P53091_512-735 2.2e-101 1 CL0023 6 512 735 I   
MCM_lid Domain P53091_749-835 2.7e-25 1 CL0671 6 749 835   
MCM Domain P38132_397-620 1.3e-103 1 CL0023 7 397 620 I   
MCM_lid Domain P38132_636-724 9.4e-23 1 CL0671 7 636 724   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
2=1-868 C CMG complex
2=1-868 C cytoplasm
2=1-868 C DNA replication preinitiation complex
2=1-868 C MCM complex
2=1-868 C nuclear pre-replicative complex
2=1-868 C nucleoplasm
2=1-868 C nucleus
2=1-868 C replication fork protection complex
2=1-868 F ATP binding
2=1-868 F chromatin binding
2=1-868 F DNA helicase activity
2=1-868 F DNA replication origin binding
2=1-868 F metal ion binding
2=1-868 F single-stranded DNA binding
2=1-868 P cellular response to DNA damage stimulus
2=1-868 P DNA strand elongation involved in DNA replication
2=1-868 P DNA unwinding involved in DNA replication
2=1-868 P double-strand break repair via break-induced replication
2=1-868 P mitotic DNA replication initiation
2=1-868 P negative regulation of DNA helicase activity
2=1-868 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
3=1-971 C chromosome, telomeric region
3=1-971 C CMG complex
3=1-971 C cytoplasm
3=1-971 C DNA replication preinitiation complex
3=1-971 C MCM complex
3=1-971 C nuclear pre-replicative complex
3=1-971 C nucleoplasm
3=1-971 C nucleus
3=1-971 C replication fork protection complex
3=1-971 F ATP binding
3=1-971 F chromatin binding
3=1-971 F DNA helicase activity
3=1-971 F DNA replication origin binding
3=1-971 F MCM complex binding
3=1-971 F single-stranded DNA binding
3=1-971 P chromatin silencing at telomere
3=1-971 P DNA replication initiation
3=1-971 P DNA strand elongation involved in DNA replication
3=1-971 P double-strand break repair via break-induced replication
3=1-971 P mitotic DNA replication initiation
3=1-971 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
3=1-971 P silent mating-type cassette heterochromatin assembly
4=1-933 C CMG complex
4=1-933 C cytoplasm
4=1-933 C DNA replication preinitiation complex
4=1-933 C MCM complex
4=1-933 C MCM core complex
4=1-933 C nuclear pre-replicative complex
4=1-933 C nuclear replication fork
4=1-933 C nucleoplasm
4=1-933 C nucleus
4=1-933 C replication fork protection complex
4=1-933 F ATP binding
4=1-933 F DNA helicase activity
4=1-933 F DNA replication origin binding
4=1-933 F single-stranded DNA binding
4=1-933 P DNA replication initiation
4=1-933 P DNA strand elongation involved in DNA replication
4=1-933 P DNA unwinding involved in DNA replication
4=1-933 P double-strand break repair via break-induced replication
4=1-933 P mitotic DNA replication initiation
4=1-933 P nuclear DNA replication
4=1-933 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
4=1-933 P protein hexamerization
5=1-775 C CMG complex
5=1-775 C cytoplasm
5=1-775 C DNA replication preinitiation complex
5=1-775 C MCM complex
5=1-775 C nuclear chromosome, telomeric region
5=1-775 C nuclear pre-replicative complex
5=1-775 C nucleoplasm
5=1-775 C nucleus
5=1-775 C replication fork protection complex
5=1-775 F ATP binding
5=1-775 F chromatin binding
5=1-775 F DNA helicase activity
5=1-775 F DNA replication origin binding
5=1-775 F single-stranded DNA binding
5=1-775 P chromatin silencing at telomere
5=1-775 P DNA replication initiation
5=1-775 P double-strand break repair via break-induced replication
5=1-775 P heterochromatin assembly
5=1-775 P negative regulation of chromatin silencing at telomere
5=1-775 P nuclear DNA replication
5=1-775 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
5=1-775 P regulation of DNA-dependent DNA replication initiation
6=1-1017 C CMG complex
6=1-1017 C cytoplasm
6=1-1017 C DNA replication preinitiation complex
6=1-1017 C MCM complex
6=1-1017 C MCM core complex
6=1-1017 C nuclear pre-replicative complex
6=1-1017 C nucleoplasm
6=1-1017 C nucleus
6=1-1017 C replication fork protection complex
6=1-1017 F ATP binding
6=1-1017 F DNA replication origin binding
6=1-1017 F single-stranded DNA binding
6=1-1017 F single-stranded DNA helicase activity
6=1-1017 P DNA replication initiation
6=1-1017 P DNA strand elongation involved in DNA replication
6=1-1017 P DNA unwinding involved in DNA replication
6=1-1017 P double-strand break repair via break-induced replication
6=1-1017 P mitotic DNA replication
6=1-1017 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
7=1-845 C chromosome, telomeric region
7=1-845 C CMG complex
7=1-845 C cytoplasm
7=1-845 C DNA replication preinitiation complex
7=1-845 C MCM complex
7=1-845 C MCM core complex
7=1-845 C nuclear pre-replicative complex
7=1-845 C nucleoplasm
7=1-845 C nucleus
7=1-845 C replication fork protection complex
7=1-845 F ATP binding
7=1-845 F chromatin binding
7=1-845 F DNA replication origin binding
7=1-845 F MCM complex binding
7=1-845 F single-stranded DNA binding
7=1-845 F single-stranded DNA helicase activity
7=1-845 P chromatin silencing at telomere
7=1-845 P DNA replication initiation
7=1-845 P DNA strand elongation involved in DNA replication
7=1-845 P DNA unwinding involved in DNA replication
7=1-845 P double-strand break repair via break-induced replication
7=1-845 P nuclear DNA replication
7=1-845 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
7=1-845 P silent mating-type cassette heterochromatin assembly
Sequences
Download file with secondary structure created by Stride  
6sko.pdb1.pdb:   [ download sequences in FASTA format ]
I (dna): 
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2 (protein): 
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3 (protein): 
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4 (protein): 
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5 (protein): 
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6 (protein): 
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7 (protein): 
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