General information
PDB ID 6T7C
Title STRUCTURE OF TWO COPIES OF HUMAN SOX11 TRANSCRIPTION FACTOR IN COMPLEX WITH A NUCLEOSOME
PDB header NUCLEAR PROTEIN
Date 2019-10-21
Experimental method ELECTRON MICROSCOPY
Resolution (A) 4
Kind dna
Organism HOMO SAPIENS, SYNTHETIC CONSTRUCT
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6t7c.pdb ABCDEFGHKL IJ 0
Biounits:
6t7c.pdb1.pdb ABCDEFGHKL IJ 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Histone Domain Q71DI3_40-132 1.3e-45 1 CL0012 A 37 131 IJ  H-Bb H-Mj S-Bb L-Bb L-Mn 
CENP-T_C Domain P62805_19-99 5e-08 1 CL0012 B 24 98 IJ  H-Bb H-Mj S-Bb L-Bb 
Histone Domain P04908_16-91 3.3e-16 1 CL0012 C 13 90 IJ  H-Bb S-Bb L-Bb 
Histone Domain O60814_32-102 4.6e-22 1 CL0012 D 27 98 IJ  S-Bb L-Bb 
Histone Domain Q71DI3_40-132 2.8e-45 1 CL0012 E 38 131 IJ  H-Bb L-Bb L-Mn 
CENP-T_C Domain P62805_19-99 5.2e-08 1 CL0012 F 20 98 IJ  H-Bb L-Bb 
Histone Domain P04908_16-91 3.3e-16 1 CL0012 G 13 90 IJ  H-Bb S-Bb L-Bb 
Histone Domain O60814_32-102 4.6e-22 1 CL0012 H 27 98 IJ  H-Bb S-Bb L-Bb 
HMG_box Domain P35716_49-117 1.9e-27 1 CL0114 K 49 117 J  L-Bb 
HMG_box Domain P35716_49-117 1.5e-27 1 CL0114 L 49 117   
Histone_H2A_C Family P04908_92-119 2.4e-17 1 No_clan C 91 118   
Histone_H2A_C Family P04908_92-119 2.4e-17 1 No_clan G 91 118   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/E=1-136 C extracellular exosome
A/E=1-136 C extracellular region
A/E=1-136 C nucleoplasm
A/E=1-136 C nucleosome
A/E=1-136 C nucleus
A/E=1-136 F DNA binding
A/E=1-136 F protein heterodimerization activity
A/E=1-136 P blood coagulation
A/E=1-136 P cellular protein metabolic process
A/E=1-136 P chromatin organization
A/E=1-136 P interleukin-7-mediated signaling pathway
A/E=1-136 P negative regulation of gene expression, epigenetic
A/E=1-136 P nucleosome assembly
A/E=1-136 P rDNA heterochromatin assembly
A/E=1-136 P regulation of gene silencing by miRNA
A/E=1-136 P regulation of megakaryocyte differentiation
B/F=1-103 C extracellular exosome
B/F=1-103 C extracellular region
B/F=1-103 C host cell nucleus
B/F=1-103 C membrane
B/F=1-103 C nuclear chromosome
B/F=1-103 C nuclear chromosome, telomeric region
B/F=1-103 C nuclear nucleosome
B/F=1-103 C nucleoplasm
B/F=1-103 C nucleosome
B/F=1-103 C nucleus
B/F=1-103 C protein-containing complex
B/F=1-103 F DNA binding
B/F=1-103 F protein domain specific binding
B/F=1-103 F protein heterodimerization activity
B/F=1-103 F RNA binding
B/F=1-103 P cellular protein metabolic process
B/F=1-103 P CENP-A containing nucleosome assembly
B/F=1-103 P DNA replication-dependent nucleosome assembly
B/F=1-103 P DNA replication-independent nucleosome assembly
B/F=1-103 P DNA-templated transcription, initiation
B/F=1-103 P double-strand break repair via nonhomologous end joining
B/F=1-103 P negative regulation of gene expression, epigenetic
B/F=1-103 P negative regulation of megakaryocyte differentiation
B/F=1-103 P nucleosome assembly
B/F=1-103 P rDNA heterochromatin assembly
B/F=1-103 P regulation of gene silencing by miRNA
B/F=1-103 P regulation of megakaryocyte differentiation
B/F=1-103 P telomere capping
B/F=1-103 P telomere organization
C/G=1-130 C extracellular exosome
C/G=1-130 C nuclear chromatin
C/G=1-130 C nucleosome
C/G=1-130 C nucleus
C/G=1-130 F DNA binding
C/G=1-130 F protein heterodimerization activity
C/G=1-130 P chromatin organization
C/G=1-130 P chromatin silencing
C/G=1-130 P negative regulation of cell population proliferation
D/H=1-126 C cytosol
D/H=1-126 C extracellular space
D/H=1-126 C nucleoplasm
D/H=1-126 C nucleosome
D/H=1-126 C nucleus
D/H=1-126 F DNA binding
D/H=1-126 F protein heterodimerization activity
D/H=1-126 P antibacterial humoral response
D/H=1-126 P antimicrobial humoral immune response mediated by antimicrobial peptide
D/H=1-126 P defense response to Gram-negative bacterium
D/H=1-126 P defense response to Gram-positive bacterium
D/H=1-126 P innate immune response in mucosa
D/H=1-126 P killing of cells of other organism
D/H=1-126 P nucleosome assembly
D/H=1-126 P protein ubiquitination
K/L=33-138 C nuclear chromatin
K/L=33-138 C nucleoplasm
K/L=33-138 C nucleus
K/L=33-138 C transcription regulator complex
K/L=33-138 F DNA-binding transcription activator activity, RNA polymerase II-specific
K/L=33-138 F DNA-binding transcription factor activity
K/L=33-138 F DNA-binding transcription factor activity, RNA polymerase II-specific
K/L=33-138 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
K/L=33-138 F transcription regulatory region sequence-specific DNA binding
K/L=33-138 P anatomical structure morphogenesis
K/L=33-138 P cardiac ventricle formation
K/L=33-138 P cell differentiation
K/L=33-138 P closure of optic fissure
K/L=33-138 P cornea development in camera-type eye
K/L=33-138 P embryonic digestive tract morphogenesis
K/L=33-138 P embryonic skeletal system morphogenesis
K/L=33-138 P eyelid development in camera-type eye
K/L=33-138 P glial cell development
K/L=33-138 P glial cell proliferation
K/L=33-138 P hard palate development
K/L=33-138 P kidney development
K/L=33-138 P lens morphogenesis in camera-type eye
K/L=33-138 P limb bud formation
K/L=33-138 P lung morphogenesis
K/L=33-138 P negative regulation of cell death
K/L=33-138 P negative regulation of gene expression
K/L=33-138 P negative regulation of glial cell proliferation
K/L=33-138 P negative regulation of lymphocyte proliferation
K/L=33-138 P negative regulation of transcription by RNA polymerase II
K/L=33-138 P negative regulation of transcription regulatory region DNA binding
K/L=33-138 P neural crest cell development
K/L=33-138 P neural tube formation
K/L=33-138 P neuroepithelial cell differentiation
K/L=33-138 P neuron differentiation
K/L=33-138 P noradrenergic neuron differentiation
K/L=33-138 P oligodendrocyte development
K/L=33-138 P outflow tract morphogenesis
K/L=33-138 P positive regulation of BMP signaling pathway
K/L=33-138 P positive regulation of cell population proliferation
K/L=33-138 P positive regulation of gene expression
K/L=33-138 P positive regulation of hippo signaling
K/L=33-138 P positive regulation of hormone secretion
K/L=33-138 P positive regulation of lens epithelial cell proliferation
K/L=33-138 P positive regulation of neurogenesis
K/L=33-138 P positive regulation of neuron differentiation
K/L=33-138 P positive regulation of ossification
K/L=33-138 P positive regulation of osteoblast differentiation
K/L=33-138 P positive regulation of stem cell proliferation
K/L=33-138 P positive regulation of transcription by RNA polymerase II
K/L=33-138 P positive regulation of transcription, DNA-templated
K/L=33-138 P regulation of transcription, DNA-templated
K/L=33-138 P regulation of transforming growth factor beta receptor signaling pathway
K/L=33-138 P signal transduction involved in cell cycle checkpoint
K/L=33-138 P skeletal muscle cell differentiation
K/L=33-138 P skeletal system development
K/L=33-138 P soft palate development
K/L=33-138 P somite development
K/L=33-138 P spinal cord development
K/L=33-138 P sympathetic nervous system development
K/L=33-138 P ventricular septum morphogenesis
Sequences
Download file with secondary structure created by Stride  
6t7c.pdb1.pdb:   [ download sequences in FASTA format ]
I (dna): 
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J (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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E (protein): 
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F (protein): 
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G (protein): 
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H (protein): 
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K (protein): 
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L (protein): 
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