General information
PDB ID 6WGG
Title ATOMIC MODEL OF PRE-INSERTION MUTANT OCCM-DNA COMPLEX(ORC-CDC6-CDT1- MCM2-7 WITH MCM6 WHD TRUNCATION)
PDB header REPLICATION/DNA
Date 2020-04-05
Experimental method ELECTRON MICROSCOPY
Resolution (A) 8.1
Kind dna
Organism SACCHAROMYCES CEREVISIAE
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6wgg.pdb 89ABCEDF234567 GH 0
Biounits:
6wgg.pdb1.pdb 89ABCEDF234567 GH 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
MCM Domain P29469_480-703 2.4e-97 1 CL0023 2 480 703   
MCM_OB Domain P29469_305-434 2.3e-34 1 CL0021 2 305 452   
MCM_lid Domain P29469_761-845 4.7e-26 1 CL0671 2 761 845   
MCM_N Domain P29469_208-299 9.8e-12 1 No_clan 2 208 299   
MCM Domain P24279_346-569 1.8e-97 1 CL0023 3 346 652   
MCM_OB Domain P24279_166-302 1.4e-32 1 CL0021 3 166 319   
MCM_lid Domain P24279_654-737 1.4e-23 1 CL0671 3 654 737   
MCM_N Domain P24279_25-159 5.1e-07 1 No_clan 3 25 212   
MCM Domain P30665_505-728 1.6e-99 1 CL0023 4 505 728   
MCM_OB Domain P30665_313-443 3.1e-36 1 CL0021 4 313 459   
MCM_lid Domain P30665_745-833 3.8e-21 1 CL0671 4 745 833   
MCM_N Domain P30665_191-307 5.1e-16 1 No_clan 4 191 307   
MCM Domain P29496_353-553 4.7e-82 1 CL0023 5 353 600   
MCM_OB Domain P29496_146-302 3.4e-38 1 CL0021 5 146 324   
MCM_lid Domain P29496_597-688 1.7e-26 1 CL0671 5 597 688   
MCM_N Domain P29496_28-110 1.5e-16 1 No_clan 5 28 141   
MCM Domain P53091_512-735 1.2e-103 1 CL0023 6 512 735   
MCM_OB Domain P53091_275-405 1.5e-40 1 CL0021 6 275 405   
MCM_lid Domain P53091_749-835 1.6e-26 1 CL0671 6 749 834   
MCM_N Domain P53091_112-269 2.8e-22 1 No_clan 6 112 269   
MCM Domain P38132_397-620 6.6e-103 1 CL0023 7 397 620   
MCM_OB Domain P38132_226-359 4.5e-32 1 CL0021 7 226 378   
MCM_lid Domain P38132_636-724 3.2e-23 1 CL0671 7 636 724   
MCM_N Domain P38132_18-206 1.9e-14 1 No_clan 7 19 206   
AAA_22 Domain P09119_97-267 2.6e-13 1 CL0023 9 97 267   
Cdc6_C Domain P09119_418-498 3.6e-06 1 CL0123 9 418 500   
AAA_lid_10 Domain P54784_637-730 8.5e-35 1 CL0671 A 637 775   
AAA Domain P54784_475-621 5.5e-19 1 CL0023 A 475 621   
ORC_WH_C Domain P54790_484-613 3.1e-16 1 CL0123 C 484 613   
AAA_22 Domain P54791_47-185 7e-05 0 CL0023 D 91 257   
AAA_22 Domain P50874_28-177 1.6e-06 1 CL0023 E 28 177 G  H-Bb 
ORC2 Family P32833_259-608 4.6e-101 1 No_clan B 259 608 H  H-Bb L-Bb 
ORC4_C Family P54791_286-517 1.6e-36 1 CL0671 D 286 517 HG  H-Bb H-Mj L-Bb 
ORC5_C Family P50874_187-337 1.1e-24 1 No_clan E 187 374 H  H-Bb 
ORC5_C Family P50874_333-421 1.5e-23 1 No_clan E 352 474 H  L-Bb 
ORC6 Family P38826_271-416 1.4e-45 1 No_clan F 271 416   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
2=1-868 C CMG complex
2=1-868 C cytoplasm
2=1-868 C DNA replication preinitiation complex
2=1-868 C MCM complex
2=1-868 C nuclear pre-replicative complex
2=1-868 C nucleoplasm
2=1-868 C nucleus
2=1-868 C replication fork protection complex
2=1-868 F ATP binding
2=1-868 F chromatin binding
2=1-868 F DNA helicase activity
2=1-868 F DNA replication origin binding
2=1-868 F metal ion binding
2=1-868 F single-stranded DNA binding
2=1-868 P cellular response to DNA damage stimulus
2=1-868 P DNA strand elongation involved in DNA replication
2=1-868 P DNA unwinding involved in DNA replication
2=1-868 P double-strand break repair via break-induced replication
2=1-868 P mitotic DNA replication initiation
2=1-868 P negative regulation of DNA helicase activity
2=1-868 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
3=1-971 C chromosome, telomeric region
3=1-971 C CMG complex
3=1-971 C cytoplasm
3=1-971 C DNA replication preinitiation complex
3=1-971 C MCM complex
3=1-971 C nuclear pre-replicative complex
3=1-971 C nucleoplasm
3=1-971 C nucleus
3=1-971 C replication fork protection complex
3=1-971 F ATP binding
3=1-971 F chromatin binding
3=1-971 F DNA helicase activity
3=1-971 F DNA replication origin binding
3=1-971 F MCM complex binding
3=1-971 F single-stranded DNA binding
3=1-971 P chromatin silencing at telomere
3=1-971 P DNA replication initiation
3=1-971 P DNA strand elongation involved in DNA replication
3=1-971 P double-strand break repair via break-induced replication
3=1-971 P mitotic DNA replication initiation
3=1-971 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
3=1-971 P silent mating-type cassette heterochromatin assembly
4=1-933 C CMG complex
4=1-933 C cytoplasm
4=1-933 C DNA replication preinitiation complex
4=1-933 C MCM complex
4=1-933 C MCM core complex
4=1-933 C nuclear pre-replicative complex
4=1-933 C nuclear replication fork
4=1-933 C nucleoplasm
4=1-933 C nucleus
4=1-933 C replication fork protection complex
4=1-933 F ATP binding
4=1-933 F DNA helicase activity
4=1-933 F DNA replication origin binding
4=1-933 F single-stranded DNA binding
4=1-933 P DNA replication initiation
4=1-933 P DNA strand elongation involved in DNA replication
4=1-933 P DNA unwinding involved in DNA replication
4=1-933 P double-strand break repair via break-induced replication
4=1-933 P mitotic DNA replication initiation
4=1-933 P nuclear DNA replication
4=1-933 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
4=1-933 P protein hexamerization
5=1-775 C CMG complex
5=1-775 C cytoplasm
5=1-775 C DNA replication preinitiation complex
5=1-775 C MCM complex
5=1-775 C nuclear chromosome, telomeric region
5=1-775 C nuclear pre-replicative complex
5=1-775 C nucleoplasm
5=1-775 C nucleus
5=1-775 C replication fork protection complex
5=1-775 F ATP binding
5=1-775 F chromatin binding
5=1-775 F DNA helicase activity
5=1-775 F DNA replication origin binding
5=1-775 F single-stranded DNA binding
5=1-775 P chromatin silencing at telomere
5=1-775 P DNA replication initiation
5=1-775 P double-strand break repair via break-induced replication
5=1-775 P heterochromatin assembly
5=1-775 P negative regulation of chromatin silencing at telomere
5=1-775 P nuclear DNA replication
5=1-775 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
5=1-775 P regulation of DNA-dependent DNA replication initiation
6=1-1017 C CMG complex
6=1-1017 C cytoplasm
6=1-1017 C DNA replication preinitiation complex
6=1-1017 C MCM complex
6=1-1017 C MCM core complex
6=1-1017 C nuclear pre-replicative complex
6=1-1017 C nucleoplasm
6=1-1017 C nucleus
6=1-1017 C replication fork protection complex
6=1-1017 F ATP binding
6=1-1017 F DNA replication origin binding
6=1-1017 F single-stranded DNA binding
6=1-1017 F single-stranded DNA helicase activity
6=1-1017 P DNA replication initiation
6=1-1017 P DNA strand elongation involved in DNA replication
6=1-1017 P DNA unwinding involved in DNA replication
6=1-1017 P double-strand break repair via break-induced replication
6=1-1017 P mitotic DNA replication
6=1-1017 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
7=1-845 C chromosome, telomeric region
7=1-845 C CMG complex
7=1-845 C cytoplasm
7=1-845 C DNA replication preinitiation complex
7=1-845 C MCM complex
7=1-845 C MCM core complex
7=1-845 C nuclear pre-replicative complex
7=1-845 C nucleoplasm
7=1-845 C nucleus
7=1-845 C replication fork protection complex
7=1-845 F ATP binding
7=1-845 F chromatin binding
7=1-845 F DNA replication origin binding
7=1-845 F MCM complex binding
7=1-845 F single-stranded DNA binding
7=1-845 F single-stranded DNA helicase activity
7=1-845 P chromatin silencing at telomere
7=1-845 P DNA replication initiation
7=1-845 P DNA strand elongation involved in DNA replication
7=1-845 P DNA unwinding involved in DNA replication
7=1-845 P double-strand break repair via break-induced replication
7=1-845 P nuclear DNA replication
7=1-845 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
7=1-845 P silent mating-type cassette heterochromatin assembly
8=1-604 C cytoplasm
8=1-604 C nuclear pre-replicative complex
8=1-604 C nucleus
8=1-604 F DNA replication origin binding
8=1-604 P cell division
8=1-604 P double-strand break repair via break-induced replication
8=1-604 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
8=1-604 P regulation of DNA-dependent DNA replication initiation
9=1-513 C chromosome
9=1-513 C cytoplasm
9=1-513 C DNA replication preinitiation complex
9=1-513 C nuclear pre-replicative complex
9=1-513 C nucleus
9=1-513 F ATP binding
9=1-513 F ATPase activity
9=1-513 F chromatin binding
9=1-513 F DNA replication origin binding
9=1-513 F GTP binding
9=1-513 F GTPase activity
9=1-513 P cell division
9=1-513 P DNA replication initiation
9=1-513 P G1/S transition of mitotic cell cycle
9=1-513 P mitotic cell cycle
9=1-513 P mitotic DNA replication checkpoint
9=1-513 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
9=1-513 P regulation of chromatin silencing at telomere
9=1-513 P regulation of DNA-dependent DNA replication initiation
A=1-913 C DNA replication preinitiation complex
A=1-913 C nuclear chromosome, telomeric region
A=1-913 C nuclear origin of replication recognition complex
A=1-913 C nuclear pre-replicative complex
A=1-913 C nucleus
A=1-913 F ATP binding
A=1-913 F ATPase activity
A=1-913 F chromatin binding
A=1-913 F DNA replication origin binding
A=1-913 F metal ion binding
A=1-913 F nucleosome binding
A=1-913 P DNA replication initiation
A=1-913 P maintenance of rDNA
A=1-913 P mitotic cell cycle
A=1-913 P mitotic DNA replication checkpoint
A=1-913 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
A=1-913 P silent mating-type cassette heterochromatin assembly
B=1-620 C chromosome, telomeric region
B=1-620 C DNA replication preinitiation complex
B=1-620 C nuclear origin of replication recognition complex
B=1-620 C nuclear pre-replicative complex
B=1-620 F chromatin binding
B=1-620 F DNA replication origin binding
B=1-620 P chromatin silencing at telomere
B=1-620 P DNA replication initiation
B=1-620 P histone H3-K4 methylation
B=1-620 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
B=1-620 P silent mating-type cassette heterochromatin assembly
C=1-616 C DNA replication preinitiation complex
C=1-616 C nuclear origin of replication recognition complex
C=1-616 C nuclear pre-replicative complex
C=1-616 F chromatin binding
C=1-616 F DNA replication origin binding
C=1-616 P DNA replication initiation
C=1-616 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
C=1-616 P silent mating-type cassette heterochromatin assembly
D=1-529 C DNA replication preinitiation complex
D=1-529 C nuclear origin of replication recognition complex
D=1-529 C nuclear pre-replicative complex
D=1-529 F DNA replication origin binding
D=1-529 P DNA replication initiation
D=1-529 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
D=1-529 P silent mating-type cassette heterochromatin assembly
E=1-479 C DNA replication preinitiation complex
E=1-479 C nuclear origin of replication recognition complex
E=1-479 C nuclear pre-replicative complex
E=1-479 F ATP binding
E=1-479 F DNA replication origin binding
E=1-479 P DNA replication initiation
E=1-479 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
E=1-479 P regulation of chromatin silencing at telomere
E=1-479 P silent mating-type cassette heterochromatin assembly
F=1-435 C DNA replication preinitiation complex
F=1-435 C nuclear origin of replication recognition complex
F=1-435 C nuclear pre-replicative complex
F=1-435 F DNA replication origin binding
F=1-435 P DNA replication initiation
F=1-435 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
F=1-435 P silent mating-type cassette heterochromatin assembly
Sequences
Download file with secondary structure created by Stride  
6wgg.pdb1.pdb:   [ download sequences in FASTA format ]
G (dna): 
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H (dna): 
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2 (protein): 
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3 (protein): 
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4 (protein): 
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5 (protein): 
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6 (protein): 
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7 (protein): 
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8 (protein): 
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9 (protein): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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E (protein): 
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F (protein): 
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